Steelers vs. 49ers Week 3 Prediction

Steelers vs. 49ers, 9/22/19 NFL Week 3 Predictions & Betting Odds

Mason Rudolph will lead the Steelers into Santa Clara on Sunday afternoon in search of the team’s first win. Meanwhile, the 49ers will look to improve to 3-0 on the year and are listed as 6.5-point favorites. Will San Francisco cover?

Game Snapshot

485 Pittsburgh Steelers (+6.5) at 486 San Francisco 49ers (-6.5); O/U 44

4:25 p.m. ET, Sunday, September 22, 2019

Levi’s Stadium, Santa Clara, CA

Public Betting Trends

According to our NFL Football Public Betting Chart page, the 49ers are receiving 60% of the betting tickets from online sportsbooks.

Pittsburgh Steelers Fantasy Spin

James Conner (knee) is good to go for the Steelers' Week 3 matchup against the 49ers. Conner practiced in full on Thursday and Friday. He wasn't listed on the team's final injury report. Still, it wouldn't be surprising if he shares more snaps than usual at less than 100% with Jaylen Samuels. Conner is best approached as a low-end RB2 without Ben Roethlisberger (elbow, IR) under center. The 49ers' vastly-improved front seven allowed a combined 146 rushing yards to the Buccaneers and Bengals in Weeks 1 and 2.

San Francisco 49ers Fantasy Spin

Nick Bosa (ankle) is questionable for the 49ers' Week 3 matchup against the Steelers. Bosa is expected to again play through his injury designation. The No. 2 overall pick has been brilliant to start the season, racking up 10 pressures in two weeks. Only eight defenders in the entire league have more.

NFL Betting Trends

Pittsburgh

The Steelers are 1-3-1 against the spread in their last five road games and 2-6-1 at the betting window in their last nine games overall.

San Francisco

The 49ers have failed to cover the spread in 16 of their last 23 home games.

Prediction

The 49ers were small underdogs in Week 1 when they knocked off the Bucs and beat the Bengals in Week 2 with the line set as a pick’em. Now, with the injury to Ben Roethlisberger, the 49ers are a sizable home favorite. This line is inflated and I like backing a desperate Pittsburgh team that might get a youthful punch in the arm with Rudolph starting in place of the injured Big Ben. For as good as San Francisco has looked offensively, its defense still has major question marks.

NFL Week 3 Prediction: Pittsburgh Steelers +6.5

Recent NFL Discussions

Loading...

NFL Predictions & Picks

Thumbnail Falcons vs. Panthers Spread Prediction The Panthers look to get back to .500 with a win over the struggling Falcons on Thursday night in a matchup of NFC South rivals. That said, will Atlanta pull...
Thumbnail Falcons vs. Panthers Total Prediction NFC South rivals square in Charlotte on Thursday night when the Panthers host the Falcons at 8:20 p.m. ET. With the total sitting at 51, will these teams score...
Thumbnail MNF Bears vs. Rams Spread Prediction The Rams opened as 7-point home favorites versus the Bears for the teams’ Monday Night Football matchup at 8:15 p.m. ET tonight but the line dropped a full...
Thumbnail Bears vs. Rams MNF Total Prediction The total for Monday Night Football’s matchup between the Bears and Rams sits at 44.5 points after opening as high as 47 at some books. Is the under the best play...
Thumbnail NFL Week 8 Openign Line Report Week 7 isn’t completely in the books yet, as the Rams still need to host the Bears on Monday Night Football. That said, here’s an early look at the point spreads,...

NFL Headlines