Louisville vs. Clemson Pick

College Football Week 5 Pick: Louisville vs. Clemson 10/1/16

Will Louisville and Clemson score enough points to push the total over for bettors at 8:00PM ET on Saturday night?

According to oddsmakers from online sports book BetDSI, the Cardinals are 1.5-point road favorites versus the Tigers while the over/under currently sits at 68 points. Clemson opened as a 3.5-point favorite before the number jumped the fence, while the total opened at 67.5 before it was bet up a half point to 68.

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LOUISVILLE: The Cardinals are aoff to a perfect 4-0 start and are 3-0-1 against the spread this season after pushing as a 31-point favorite last week in a 59-28 win over Marshall. Heisman leader Lamar Jackson leads the team in passing (1,330 yards), rushing (526 yards), and total touchdowns (12). He's been far and away the most impressive player in college football this season.

CLEMSON: The Tigers are 4-0 on the year and 2-2 against the spread after covering as a 10.5-point road favorite last week in a 26-7 victory over Georgia Tech. Deshaun Watson completed 32-of-48 passes for 304 yards with two touchdowns and an interception in the win, while Ray-Ray McCloud caught eight passes for 101 yards in the victory.

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OUR PICK: The over is 4-0 in the Cardinals' last four games overall and 4-0 in their last four road games. The over is also 5-0 in Louisville's last five conference games, is 6-1 in its last seven games coming off a win and 4-1 in its last five games versus a team with a winning record. On the other side, the over is 4-0 in the Tigers' last four games in October and 5-2 in their last seven games after allowing less than 170 yards passing in their previous game.



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