Mississippi State vs. Southern Miss Pick

College Football Week 1 Mississippi State vs. Southern Miss Free Pick

Mississippi State will open its 2015 season on the road tonight when it visits Hattiesburg to take on Southern Miss at 10:00PM ET.

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According to oddsmakers from online sports book GT Bets, the Bulldogs are 21-point road favorites over the Golden Eagles for tonight's game, while the over/under is sitting at 61 points.

Quarterback Dak Prescott leads a Mississippi State team that crushed Southern Miss, 49-0 last year. The Bulldogs were a machine last year, finishing 10th in the nation in total yards per game.

Prescott threw for 3,449 yards and 27 TDs, while rushing for 986 yards and 14 scores. Southern Miss is headed for a quarterback rotation, which is never a good thing.

COLLEGE FOOTBALL WEEK 1 FREE PICK: MISSISSIPPI STATE -21 OVER SOUTHERN MISS

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