Notre Dame vs. Louisville Prediction

Notre Dame vs. Louisville, 2/23/21 College Basketball Betting Predictions

ACC foes clash in Louisville on Tuesday night when the Cardinals host the Notre Dame Fighting Irish at 7:00 p.m. ET. Will the Cardinals rebound from their blowout loss to UNC over the weekend to cover as a 4-point home favorite tonight?

Game Snapshot

623 Notre Dame Fighting Irish (+4) at 624 Louisville Cardinals (-4); o/u 141

7:00 p.m. ET, Tuesday, February 23, 2021

Venue: KFC Yum! Center, Louisville, KY

TV: ACC Network

Notre Dame vs. Louisville College Basketball Prediction

The home team is 7-3-1 against the spread in the last 11 meetings between these two teams, while the Cardinals are 7-3-1 against the number in their last 11 games at the KFC Yum! Center when facing a team that owns a losing record on the road. Louisville is also 5-1 against the spread in its last six games coming off a loss, is 5-1 against the number in its last six games following an ATS loss and 5-0 against the number in it last five games coming off a loss of more than 20 points.

The Fighting Irish, meanwhile, are 1-6 at the betting window in their last seven games when facing an opponent like Louisville that owns a winning percentage that is above .600.

COLLEGE BASKETBALL PREDICTION: LOUISVILLE CARDINALS -4

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