69 - Loyola of Chicago 111, Tennessee Tech 42, first round, 1963
58 - Kansas 110, Prairie View 52, first round, 1998
56 - Connecticut 103, Chattanooga 47, first round, 2009
49 - UCLA 109, Wyoming 60, regional semifinal, 1967
49 - Syracuse 101, Brown 52, first round, 1986
47 - Duke 101, Connecticut 54, regional championship, 1964
47 - DePaul 99, Eastern Kentucky 52, first round, 1965
47 - Duke 84, Winthrop 37, first round, 2002
46 - Kentucky 113, Mount St. Mary's, Md. 67, first round, 1995
45 - North Carolina 112, Rhode Island 67, second round, 1993

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