NEW YORK (AP) -Andy Pettitte got the warm reception he was hoping for when he made his first start after a rocky offseason. The rest of the day didn't go as planned.
Jonny Gomes homered and drove in four runs against Pettitte, and the Tampa Bay Rays beat the New York Yankees 6-3 on Saturday.
Pettitte was on a shorter-than-normal pitch count after he opened the season on the disabled list with back spasms. He lasted just five innings and was outpitched by Edwin Jackson (1-0), who allowed one run and five hits in six innings . Troy Percival pitched the ninth for his first save.
It was Pettitte's first regular-season start since he admitted using human growth hormone and accused buddy and former teammate Roger Clemens of also using HGH.
New York again was without Joe Girardi, who missed his second straight game with an upper respiratory infection.
White Sox 5, Tigers 3
DETROIT (AP) - Jim Thome hit an RBI double in the sixth inning for the White Sox's only hit off Dontrelle Willis, and Chicago beat Detroit, the only winless team in the major leagues.
Detroit is 0-5 for the first time since the Tigers dropped their first nine games in 2003 en route to an AL-record 119 losses.
Willis was wild in his debut with the Tigers, walking seven in five-plus innings. He gave up three runs in the White Sox's four-run sixth.
Brandon Inge drove in all of Detroit's runs with a two-run homer and RBI double.
Gavin Floyd (1-0) gave up three runs on six hits in six innings, walking two and striking out two.
Zach Miner (0-1) gave up one unearned run and took the loss in relief of Willis.
Athletics 6, Indians 1
OAKLAND, Calif. (AP) - Cleveland's C.C. Sabathia got roughed up in another disappointing homecoming and Dana Eveland allowed one run in seven innings to win in his Oakland debut.
Jack Cust hit a two-run double in a three-run first inning and Mark Ellis added a solo homer against Sabathia (0-1), a native of nearby Vallejo who fell to 1-4 with a 7.12 ERA in eight career starts in Oakland.
Sabathia, the reigning AL Cy Young winner, gave up four runs, six hits, and four walks in 5 1-3 innings and has a 7.59 ERA after two starts this season. He allowed three runs in the opening inning as Cleveland lost for the 18th time in its last 24 games in Oakland.
Eveland (1-0), one of the players acquired from Arizona in the Dan Haren trade, did just fine in his first appearance in front of his new fans by winning for the first time in seven career starts. He had been 0-3 with a 9.33 ERA as a starter for Milwaukee and Arizona, never lasting longer than 5 2-3 innings or allowing fewer than four runs.
Blue Jays 10, Red Sox 2
TORONTO (AP) - Frank Thomas hit a two-run homer, David Eckstein had three RBIs and the Toronto Blue Jays used a six-run eighth inning to beat Boston for the sixth straight time.
Blue Jays right-hander Jesse Litsch (1-0) allowed two runs on five hits over five innings for the win. He walked three - one intentional - and struck out two.
Boston's Clay Buchholz (0-1) gave up four runs - three earned - and six hits over five innings. The right-hander walked two and struck out seven.
Angels 2, Rangers 1
ANAHEIM, Calif. (AP) - Jered Weaver pitched seven scoreless innings, Torii Hunter and Howie Kendrick had run-scoring hits and Los Angeles beat Texas.
Weaver (1-1) allowed three hits, walked none and struck out six after losing at Minnesota in the first opening-day assignment of his career.
Weaver threw 93 pitches. Darren Oliver relieved and gave up a leadoff homer in the eighth to David Murphy. Francisco Rodriguez followed Justin Speier out of the bullpen and got three outs for his third save.
Kevin Millwood (0-2) allowed 12 hits over eight innings, going the distance for the 15th time in 317 career starts. He struck out seven and walked one. The Rangers had played an AL-record 195 consecutive regular-season games without a complete-game effort by their staff since Aug. 29, 2006, when Millwood allowed eight hits in a 9-4 win against Baltimore on Aug. 29, 2006.
Twins 6, Royals 4
MINNEAPOLIS (AP) - Justin Morneau hit his first home run of the season and drove in four runs, and Livan Hernandez won his second straight start for the Twins.
Hernandez (2-0) pitched seven solid innings as the Twins won their second consecutive game against the Royals, who started the season 3-0. Hernandez allowed four runs and seven hits. He did not walk a batter and struck out two.
Matt Guerrier worked a scoreless eighth for Minnesota and Joe Nathan the ninth to record his third save.
Kansas City led 2-0 and Gil Meche (0-1) was off to a strong start for the Royals before giving up a three-run homer to Morneau in the fourth inning.
Orioles 6, Mariners 4
BALTIMORE (AP) - Luke Scott went 3-for-3 with two RBIs, and Baltimore received solid contributions from several other newcomers in a victory over Seattle.
Matt Albers (1-0) pitched 1 2-3 innings of one-hit relief and George Sherrill worked the ninth for his third save in three tries. Albers and Scott were both obtained from Houston in the December trade that sent Miguel Tejada to the Astros, and Sherrill came from the Mariners in the February swap for Erik Bedard.
Adam Jones, also part of the Bedard trade, hit a sacrifice fly in the seventh to give Baltimore a 6-4 lead.
Baltimore took the lead with a three-run fifth inning against Miguel Batista (0-1). Mora hit a one-out single before Batista issued three straight walks to force in a run. Scott followed with an RBI single and Ramon Hernandez added a sacrifice fly to make it 5-4.

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