Cardinals vs. Padres Prediction & Odds

Cardinals vs. Padres, 9/21/22 Betting Odds, Prediction & Trends

The Cardinals were shutout last night for the second straight game and nearly for a third consecutive time, this time by the Padres.

Will their offensive struggles continue when their series in San Diego continues at 9:40 p.m. ET?

Game Matchup & Betting Odds

959 St. Louis Cardinals (+106) at 960 San Diego Padres (-124); o/u 7.5

9:40 p.m. ET, Wednesday, September 21, 2022

Petco Park, San Diego, CA

Cardinals vs. Padres Public Betting Information

As of this writing, our MLB Public Betting page shows that 65% of bets are on the Cardinals’ moneyline. That said, this page is updated frequently so make sure that you click on the link provided so that you’re getting the most updated information.

St. Louis Cardinals DFS SPIN

Paul Goldschmidt went 1-for-4 with a double in Tuesday's loss to the Padres. Goldschmidt managed the lone extra-base hit of the game for the Cardinals when he posted his 40th double of the season on Tuesday. Those 40 doubles are just three shy of the career-best mark Goldy set with the Diamondbacks way back in 2012, when he was in just his second year of big league ball. On the whole this season, Goldschmidt is slashing a gorgeous .322/.410/.598 with 35 homers, 112 RBI and six steals across 525 at-bats. He has lost none of his batting prowess with age.

San Diego Padres DFS SPIN

Jake Cronenworth went 1-for-4 with a two-run single in Tuesday's win over the Cardinals. Cronenworth got the Padres on the board with his two-run single off Adam Wainwright in the bottom of the first inning. They would end up essentially winning the contest wire-to-wire. Through 540 at-bats this season, Cronenworth is slashing .241/.335/.391 with 16 homers, 77 RBI and three steals.

Cardinals vs. Padres MLB Betting Trends

Cardinals are 0-6 in the last 6 meetings in San Diego

Over is 6-2-1 in the last 9 meetings in San Diego

Cardinals are 6-1 in the last 7 meetings


The under is 3-0-1 in the last four meetings between these two teams, is 4-0 in the Cardinals’ last four games overall and is 9-2-2 in their last 13 road games when facing a left-handed starter. On the other side, the under is 4-0 in the Padres’ last four games coming off a win, is 6-0 in their last six games versus a right-handed starter and is 6-1 in their last seven games overall.


Recent MLB Discussions

9/24 early on Sun, Sep 2022 by Timmy1961
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