White Sox vs. Yankees Prediction

White Sox vs. Yankees, 5/21/21 MLB Betting Predictions & DFS Notes

One of the more intriguing matchups this weekend in baseball will take place in the Bronx, where the Yankees will host the White Sox. Which side will take the first game of the series at 7:05 p.m. ET on Friday night?

Game Snapshot

963 Chicago White Sox (-115) at 964 New York Yankees (-105); o/u 8.5

7:05 p.m. ET, Thursday, May 21, 2021

Yankee Stadium, New York, NY

Chicago White Sox DFS Spin

Jose Abreu will not play in the White Sox' series against the Twins after being diagnosed with left ankle inflammation. Abreu suffered the injury during a slide into home plate on Sunday. The good news is X-rays came back clean and an MRI "only" showed a little inflammation. The club expects the reigning American League MVP to be back this weekend against the Yankees, although they won't rush him if he's not quite ready. Andrew Vaughn is at first base Monday, with Leury Garcia covering left field and Billy Hamilton center.

New York Yankees DFS Spin

Aaron Judge is not in the Yankees' starting lineup Thursday against the Rangers. This appears to be a routine day of rest for Judge, who's sitting on 12 home runs and an overall .294/.392/.580 batting line through 40 games played. Miguel Andujar, Brett Gardner, and Tyler Wade will start across the outfield for the Yankees in the afternoon tilt at Texas. Luke Voit is at DH, with Mike Ford covering first base.

White Sox vs. Yankees Betting Prediction

The White Sox are just 7-17 in their last 24 meetings with the Yankees in New York. The Yankees, meanwhile, are 8-3 in their last 11 games overall, are 4-1 in their last five games versus an opponent with a winning percentage above .600 and are 88-38 in their last 126 home games.

MLB BETTING PREDICTION: NEW YORK YANKEES -105

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