Astros vs. White Sox Prediction

Houston Astros vs. Chicago White Sox, 4/22/2018 Prediction & Odds

After another lopsided win on Saturday, will the Houston Astros continue to dominate the Chicago White Sox when the two meet this afternoon at 2:10PM ET.

Game Snapshot & Odds

923 Houston Astros at 924 Chicago White Sox

Sunday, April 22, 2018

2:10PM ET, Guaranteed Rate Field

TV: ATSW (Hou); NSCH (Chi)

Public Betting Trends

According to oddsmakers at YouWager, the Astros are listed as the heavy favorite on the road, as they are getting odds of -200 to win. Chicago is listed with a money line of +175 to prevail, while the over/under total for the contest has been set at 8 runs. Currently 74% of the wagers are going on the Astros on the road. This information is subject to change, however, so be sure to check out our MLB Public Betting Page for updated figures on the game.

Houston locking down opponents

The Astros picked up a 10-1 win over the White Sox on Saturday thanks to another strong start. Houston has won five straight, allowing just five runs total over those five games. The Astros are now 15-7 overall and 9-4 on the road. Houston is putting up 4.91 runs per game while allowing just 2.55 per contest this year.

Lance McCullers Jr. gets the start today for Houston. He is 2-1 through four starts with a 5.57 ERA and a 1.43 WHIP. He has allowed 13 earned runs over 21 innings and has 34 strikeouts with 11 walks.

White Sox a mess

Chicago has now been outscored by 39 runs during this six-game losing streak they are on right now. The White Sox are now just 4-13 on the season and 1-7 at home. Chicago is averaging 3.71 runs per game this season while allowing 6.65 per game.

Reynaldo Lopez gets the start today for Chicago. He is 0-2 through three starts but has just a 1.42 ERA and 1.00 WHIP. Chicago has produced only three runs over his three starts. Lopez has 11 walks and 21 strikeouts in 19 innings of work.

MLB Betting Trends


The Astros have won five straight on the road and 40 of their last 57 overall. They also are 22-5 in their last 27 after scoring 5 runs or more in their previous game.


The White Sox have now lost 13 of their last 16 overall and seven of their last eight at home. They also have lost five straight against AL West opponents.


McCullers has bad numbers, but that’s mostly due to one bad start against the Twins. He has allowed just two earned runs or less in three of his four starts. Chicago can’t hit right now, so I would expect McCullers to have another quality start while Houston finds ways to produce runs on Lopez.

The Pick: Houston Astros -200

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