Astros vs. White Sox Prediction

Houston Astros vs. Chicago White Sox, 4/21/2018 Prediction & Odds

After a dominant performance on Friday, will the Houston Astros be able to manhandle the Chicago White Sox against when they meet up tonight at 7:10PM ET?

Game Snapshot & Odds

973 Houston Astros at 974 Chicago White Sox

Saturday, April 21, 2018

7:10PM ET, Guaranteed Rate Field

TV: ATSW (Hou); NSCH (Chi)

Public Betting Trends

According to oddsmakers at YouWager, the Astros are listed as the heavy favorite on the road, as they are getting odds of -220 to win. Chicago is listed with a money line of +180 to prevail, while the over/under total for the contest has been set at 8 runs. Currently 82% of the wagers are going on the Astros on the road. This information is subject to change, however, so be sure to check out our MLB Public Betting Page for updated figures on the game.

Houston dominant on the mound

After a bit of a slump for the team, the Astros have now won four straight following a 10-0 victory on Friday. Houston has allowed just four runs over their four wins. Houston is now 14-7 overall and 8-4 on the road. The Astros are averaging 4.40 runs per game while allowing just 2.75 per contest.

Dallas Keuchel gets the start for the Astros tonight. While he hasn’t had success with his record (0-3), he has just a 3.52 ERA through four starts. His WHIP is 1.48 and he has 10 walks with 19 strikeouts over 23 innings of work.

White Sox getting lit up

Chicago has lost its last five and 10 of its last 11 after Friday’s loss. The Sox have allowed 32 runs over their last three games. Chicago is now 4-12 on the season and 1-6 at home. Chicago is scoring 4.13 runs per game while allowing 6.20 per contest.

Lucas Giolito will be starting for the White Sox this evening. He has appeared in three games this season and has an 0-2 record with a 5.50 ERA and 1.39 WHIP. He has allowed 11 earned runs over 18 innings with 12 walks and eight strikeouts.

MLB Betting Trends


The Astros are actually just 2-5 in Keuchel’s last seven starts overall and 0-5 in his last five road starts. Still, Houston has won 10 of its last 13 game 2’s in a series.


The White Sox have lost four of their last five against a left-handed starter and 22 of their last 28 Game 2’s in a series.


The Astros looked dominant on Friday and I do expect them to win, but I am not comfortable enough to pick them to win by multiple runs like I was on Friday. Keuchel has given up multiple runs in every start this year and Chicago has a lineup that can be dangerous. I don’t expect much from Giolito, but Houston’s batting order isn’t guaranteed to light up the scoreboard either.

The Pick: Houston Astros -220

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