Cardinals vs. Phillies MLB Prediction

Cardinals vs. Phillies, 4/16/21 MLB Betting Predictions & DFS Notes

A pair of teams that are off to inconsistent starts to the season will square off in Philadelphia on Friday night when the Phillies host the Cardinals at 7:05 p.m. ET. With the Phillies listed as a small home favorite and the total sitting at 8.5 runs, what’s the best play?

Game Snapshot

905 St. Louis Cardinals (+130) at 906 Philadelphia Phillies (-140); o/u 8.5

7:05 p.m. ET, Friday, April 16, 2021

Citizens Bank Park, Philadelphia, PA

St. Louis Cardinals DFS Spin

Dylan Carlson is getting the day off Wednesday afternoon against the Nationals. Lane Thomas will start in center field and bat seventh in the matinee game versus the Nats and right-hander Joe Ross. Justin Williams is in left, Tommy Edman is in right, and Matt Carpenter is at second base.

Philadelphia Phillies DFS Spin

Jean Segura went 2-for-3 with a solo home run on Wednesday against the Mets. Segura provided the only run for the Phillies with a solo blast off of David Peterson in the fifth inning that left the bat at 100.1 miles per hour. The 31-year-old added a base hit to raise his average to .295 in the early going. While Segura doesn't stand out in any particular area, he's been a solid contributor across the board and is hitting in a deep lineup that should produce plenty of run scoring opportunities.

Cardinals vs. Phillies Betting Prediction

The Cardinals are just 1-4 in their last five games against the Phillies and 2-5 in their last seven trips to Philadelphia. The Cards are also 1-4 in their last five games overall and are 1-4 in their last five road games versus a left-handed starter. The Phillies, meanwhile, are 11-2 in their last 13 games as a favorite and are 18-6 in their last 24 home games.

MLB BETTING PREDICTION: PHILADELPHIA PHILLIES -140

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