Giants vs. Diamondbacks Prediction

San Francisco Giants vs. Arizona Diamondbacks 5/15/16 MLB Predictions

The Giants are hot but with a struggling Matt Cain on the mound, will they sweep the Diamondbacks with a win today at 4:10PM ET?

According to oddsmakers from online sports book BetDSI, the Diamondbacks are -140 money line favorites over the Giants, who have odds of +125 to pull off the upset. With Cain set to face Rubby de la Rosa in the pitching matchup, the over/under currently sits at 9 runs.

Bet Today's Giants vs. Diamondbacks Game

The Giants have won four straight but they're also 0-5 in Cain's last five road starts and 0-5 in his last five starts on Sunday. They're 6-23 in Cain's last 29 starts versus a team with a losing record, 1-4 in his last five outings versus the National League West, and are 0-6 in his last six starts coming off four days of rest as well.

Continuing with those trends, San Francisco has lost 37 of Cain's last 52 starts and is 2-5 in his last seven outings after scoring five runs or more in the team's previous game. The Giants are 5-17 in Cain's last 22 outings following a quality start in his last appearance, too.

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OUR PREDICTION: The Diamondbacks are 7-1 in de la Rosa's last eight starts coming off four days of rest and are 8-3 in his last 11 outings when their opponent scores five runs or more in its previous game. Even though the Giants have beaten the D-Backs three straight games, it's difficult to pull off a sweep on the road in a four-game series. Lay the -140 on Arizona as Cain struggles in a hitter's park.


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