The opening round of the March Madness Tournament is officially underway and tonight Western Kentucky takes on Illinois in the South Region.

Let’s take a look at the odds, trends, injuries and hand out a College Basketball Free Pick for this matchup.

Bet Western Kentucky at Illinois

Tip off: 9:55PM ET

Odds: Oddsmakers from online sports book SPORTSBETTING.COM have made Illinois 5-point favorite.

Over/Under Total: 125

Top Public Betting Trends:

All games in this series since 1997

W KENTUCKY is 1-0 against the spread versus ILLINOIS since 1997

ILLINOIS is 1-0 straight up against W KENTUCKY since 1997

1 of 1 games in this series have gone UNDER THE TOTAL since 1997

Key Injuries:

W KENTUCKY

No significant injuries.

ILLINOIS

[G] 03/19/2009 - Chester Frazier downgraded to expected to miss Thursday vs. Western Kentucky. (Hand)

Free Pick: Our free pick for this game is Penn State +4.

Bet Western Kentucky at Illinois

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Posted: 3/19/09 1:15PM ET