Cardinals vs. 49ers Odds


SAN FRANCISCO, CA (The Spread) – The San Francisco 49ers look to continue their winning ways on Sunday when they host the Arizona Cardinals at 4:25PM ET on FOX.

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San Francisco is 3-2 overall, 2-1 at home and 3-2 against the spread. Arizona is 3-2 overall, 1-2 on the road and 4-1 against the spread. San Francisco has won seven of its last eight against Arizona.

Trends show that the Cardinals are just 2-7 against the spread in their last 9 against the 49ers and the road team is 11-4 against the spread in the last 15 games of this series.

According to oddsmakers from, San Francisco is the clear favorite at home, as the 49ers have odds of -11 points against the Cardinals. The over/under total for the game has been set at 41 points (View Matchup). The opening odds for this game had the 49ers as a 12.5-point favorite. The spread was never greater than that, as it fell to 11 points. The over/under total opened at 42 points and has since moved down to 41.

San Francisco is coming off a 34-3 win over Houston last week. The 49ers have won two straight by a combined score of 69-14. San Francisco is posting 321.8 yards per game on offense, while the defense is holding opponents to 302.4 yards per game. Quarterback Colin Kaepernick has thrown for 969 yards and six touchdowns while rushing for 154 yards. Frank Gore has posted 376 yards and three scores this season. NaVorro Bowman is leading the defense with 47 tackles and two sacks.

Arizona is coming off a 22-6 win over Carolina last week at home. The Cardinals have won two straight entering this game despite an offense that is averaging just 18.2 points and 306.2 yards per game. The defense is giving up 19 points and 343.4 yards per game this season. Carson Palmer has thrown for 1,185 yards and five touchdowns, but has nine interceptions. The defense has been led by Karlos Dansby, who has 46 tackles with two sacks and one interception.

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In terms of Injuries, Arizona linebacker Jasper Brinkley (groin) and safety Rashad Johnson (finger) are questionable. San Francisco cornerback Nnamdi Asomugha (ankle) and linebacker Patrick Willis (groin) are also questionable.

The Public Bets for this game are currently backing San Francisco, as the 49ers are getting 58% of the wagers with odds of -11 points against the Cardinals.

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