Mary on Thursday night.
Cuff ran for 244 yards and six touchdowns on 30 carries times and caught four passes for 52 more yards and another score for the Blue Hens (1-0).
He tied a record set in 1996 by Northern Arizona's Archie Amerson and equaled two years later by McNeese State's Jessie Burton.
Mary defensive back Robert Livingston around before reaching the end zone untouched.
Mary cut the Blue Hens' edge to 21-10 when Jake Phillips lofted a 50-yard scoring pass over Delaware's Fred Andrew to 6-foot-6 tight end Andrew Atchison on the Tribe's first possession of the third quarter. But Cuff answered with a 2-yard run to finish a 70-yard drive on which he carried seven times for 30 yards.
Cuff began the final quarter with a 20-yard scoring play for a 35-10 lead.
Phillips sneaked over from a yard out to cut the margin to 35-17, but Cuff came back with a 19-yard pass reception for a score. He added another 2-yard touchdown after Phillips found D.J. McAulay for a 17-yard TD.
Mary combined for 42 points in the first 9:43 of the fourth quarter.

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