PHILADELPHIA (AP) -Cole Hamels had an impressive outing and the Philadelphia Phillies beat the San Diego Padres 7-4 Tuesday night, denying Greg Maddux his 350th career victory.
Hamels (3-3) allowed five hits, two runs and struck out six in 7 1-3 innings. Tom Gordon worked out of a bases-loaded jam in the eighth and the Phillies scored four insurance runs in the bottom half.
Maddux (2-2) gave up three runs and eight hits in 6 1-3 innings. The four-time Cy Young award winner was trying for the third start to become the ninth pitcher in big league history to reach 350 wins.
Carlos Ruiz had a two-run double and pinch-hitter Greg Dobbs added an RBI double as the Phillies broke it open in the eighth against Glendon Rusch and Kevin Cameron.
Scott Hairston hit a pair of homers for San Diego.
Mets 5, Pirates 4, 11 innings
NEW YORK (AP) - David Wright hit a single over a pulled in outfield with the bases loaded in the 11th inning, giving New York the win over Pittsburgh after the Mets' bullpen wasted a two-hit performance by Johan Santana.
Endy Chavez singled off John Van Benschoten (0-1), Pittsburgh's sixth pitcher, leading off the 11th. Van Benschoten balked to move Chavez to second. Marlon Anderson sacrificed, and after Jose Reyes was walked intentionally - he reached in all six plate appearances - Luis Castillo walked.
Wright then hit a fly that just barely landed inside the right-field line, causing a delayed reaction from the players and fans.
Jorge Sosa (3-1), the Mets' seventh pitcher, worked one inning for the win.
The Pirates tied it in the ninth against Billy Wagner with an assist from Reyes' throwing error. It was Wagner's first blown save of the season - his first run, too, albeit unearned.
Astros 6, Diamondbacks 4
PHOENIX (AP) - Geoff Blum doubled in three runs and Houston handed Arizona only its third home loss in 13 games his season.
Max Scherzer, the Diamondbacks' 2006 first-round draft pick, made an impressive major league debut. He retired all 13 batters he faced, seven by strikeout, with a fastball that reached 98 mph. It was the most strikeouts ever by an Arizona pitcher in his first big-league game.
Jose Valverde, who led the majors with 47 saves for Arizona last year and was traded to Houston in the offseason, pitched a scoreless ninth for his fourth save in seven opportunities.
Edgar Gonzalez (1-2) allowed six runs on eight hits in 2 2-3 innings. Doug Brocail (1-0) threw 1 1-3 innings of scoreless relief to get the victory.
Brewers 10, Cubs 7
CHICAGO (AP) - Mike Cameron made an immediate impact with Milwaukee, once he had the chance.
Cameron had three hits, including a two-run single in the seventh that broke open the game, and the Brewers beat Chicago to overcome a shaky outing by Ben Sheets.
Cameron sparked a slumping offense a much-needed spark after serving a 25-game suspension for testing positive twice for a banned stimulant while with San Diego. The Brewers had a season-high 17 hits.
Sheets (4-0) issued a career-high seven walks while striking out two over five innings. He allowed four runs and three hits.
Cubs starter Jason Marquis (1-1) allowed five runs and 10 hits in five innings while walking one and striking out two.
Rockies 3, Giants 2
SAN FRANCISCO (AP) - Tim Lincecum's first loss of the year came via a debated balk call that pushed home the go-ahead run.
Chris Iannetta, who replaced the injured Troy Tulowitzki in the first, scored on that seventh-inning balk by Lincecum (4-1) that helped Colorado snap a four-game losing streak.
Iannetta also hit the first home run off Lincecum this year with a second-inning solo shot to help Aaron Cook (4-1) win his fourth straight start. Iannetta doubled to start the seventh.
Giants manager Bruce Bochy was ejected for arguing the balk, a night after Rockies skipper Clint Hurdle was thrown out for the same thing.
With Iannetta at third base with one out in the seventh inning, Giants catcher Bengie Molina appeared to ask for a timeout with Yorvit Torrealba at the plate. But plate umpire Gary Darling called a balk on Lincecum to score Iannetta for the go-ahead run and a 3-2 Rockies lead.
Nationals 6, Braves 3
WASHINGTON (AP) - Slumping Ryan Zimmerman spent some time working with Barry Larkin before the game, and then had a season-high three hits, including a homer and tiebreaking two-run double, to lead Washington past Atlanta.
Washington won for the fourth time in five games. The Braves, whose highlight was Chipper Jones' eighth homer, have lost three straight games.
Zimmerman and Nick Johnson hit consecutive solo shots in the third inning off Tom Glavine, who was coming off his first trip to the disabled list in a 22-season career. Zimmerman hadn't homered since April 2.
Then, in Washington's four-run seventh, Zimmerman hit his double off reliever Blaine Boyer (0-3), who was charged with four runs and got only one out.
Saul Rivera (2-1) got the win by pitching a scoreless seventh.
Dodgers 7, Marlins 6
MIAMI (AP) - Jeff Kent's two-out single drove in Andre Ethier to break a ninth-inning tie and help Los Angeles win its fourth straight game.
Ethier had walked with one out against Kevin Gregg (3-1) and took second on a groundout.
Joel Beimel (2-0) pitched a scoreless eighth, and Takashi Saito pitched a perfect ninth for his third save in five chances.
The Dodgers won even though Derek Lowe was unable to protect a 6-1 lead. Dan Uggla hit his fourth homer for the Marlins, and they scored three unearned runs in the fifth for a 6-all tie.
Cardinals 7, Reds 2
ST. LOUIS (AP) - Joel Pineiro pitched seven innings of one-hit ball and St. Louis jumped on rookie Johnny Cueto for seven runs in the first two innings.
Troy Glaus and Rick Ankiel combined for four hits and five RBIs their first two at-bats for the Cardinals. Skip Schumaker tied his career best with four hits and Albert Pujols walked off Josh Fogg in the eighth and has reached base safely in all 28 games.
Cueto (1-3) allowed seven runs, six earned, on eight hits in 1 2-3 innings in his sixth career start. The 22-year-old trailed 3-0 after retiring one batter and departed with a 5.40 ERA.
Pineiro (2-2) gave up a leadoff single to Corey Patterson and issued three of his four walks in the first two innings, then retired the last 12 batters in order, striking out three in seven innings.

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